How to check for insulinoma
Insulinoma is a rare pancreatic endocrine tumor that causes excessive secretion of insulin and causes symptoms of hypoglycemia. Early diagnosis and examination are crucial to treatment. This article will introduce in detail the detection methods of insulinoma, and provide structured data and analysis based on the hot medical topics on the Internet in the past 10 days.
1. Common symptoms of insulinoma
Typical symptoms of insulinoma include recurring episodes of hypoglycemia, especially on an empty stomach. Patients may experience dizziness, sweating, palpitations, confusion, or even coma. The following is a list of common symptoms of insulinoma:
| Symptoms | incidence |
|---|---|
| fasting hypoglycemia | More than 90% |
| dizziness | 80% |
| sweating | 75% |
| Palpitations | 60% |
| Confusion | 50% |
2. Examination methods for insulinoma
The diagnosis of insulinoma requires a combination of clinical symptoms and multiple examination methods. The following are commonly used inspection methods:
| Check method | purpose | Accuracy |
|---|---|---|
| 72-hour fasting test | Induce hypoglycemia and detect insulin levels | high |
| Blood tests (insulin, C-peptide, blood sugar) | Assess insulin secretion | Middle to high |
| Imaging examination (CT/MRI) | Locate tumor location | in |
| Endoscopic ultrasound (EUS) | A closer look at the pancreas | high |
| Selective Arterial Calcium Stimulation Test (ASVS) | Pinpoint tumors | high |
3. Detailed process of 72-hour fasting test
The 72-hour fasting test is the gold standard for diagnosing insulinoma. The following are the specific steps of the test:
| time | Operation | Things to note |
|---|---|---|
| 8 hours before test | fasting | Drinkable water |
| every 6 hours | Test blood sugar and insulin | record symptoms |
| When blood sugar ≤45mg/dL | Take blood test immediately | Terminate test |
| After the test | Give glucose | Observe closely |
4. Comparison of imaging examinations
The detection rates of insulinoma vary with different imaging examinations:
| Check type | Detection rate | Advantages | Disadvantages |
|---|---|---|---|
| CT scan | 30-40% | Fast and popular | Low sensitivity to small tumors |
| CT enhanced | 60-70% | Show rich blood vessels | Need contrast agent |
| MRI | 70-80% | No radiation | High cost |
| EUS | 80-90% | High resolution | Invasive |
5. Popular medical topics on the Internet in the past 10 days
According to hot discussions in the medical and health field across the Internet, the following are high-profile topics related to endocrine tumors:
| topic | heat index | Related diseases |
|---|---|---|
| New technology for rare disease diagnosis | 9.2 | Insulinoma etc. |
| Artificial Intelligence Assisted Imaging Diagnosis | 8.7 | pancreatic tumors |
| Differential diagnosis of hypoglycemia | 8.5 | Insulinoma |
| Progress in minimally invasive surgical treatment | 8.3 | pancreatic endocrine tumor |
6. Differential diagnosis of insulinoma
Insulinoma needs to be distinguished from other diseases that cause hypoglycemia:
| disease | Key points for identification |
|---|---|
| insulin autoimmune syndrome | Presence of insulin antibodies |
| noninsulinoma pancreatogenic hypoglycemia syndrome | No evidence of tumor |
| drug-induced hypoglycemia | Have a history of using hypoglycemic drugs |
| Other endocrine tumors | Different hormone profiles |
7. Summary
The diagnosis of insulinoma requires a combination of clinical symptoms, biochemical tests, and imaging tests. The 72-hour fasting test is the gold standard for diagnosis, while EUS and ASVS can improve the accuracy of tumor localization. With the development of medical technology, artificial intelligence-assisted diagnosis and minimally invasive surgery have become popular research directions. For patients with repeated episodes of hypoglycemia, they should promptly seek medical attention for systemic examination to avoid delaying treatment.
This article combines the latest medical hot spots and structured data to comprehensively introduce the detection methods of insulinoma, hoping to provide valuable reference information for patients and medical workers.
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